About Me
Dr. Daryl Thornton is associate professor in the Department of Internal Medicine in The MetroHealth System where he is a pulmonologist and intensivist. Dr. Thornton is Director of the Medical Intensive Care Unit. His research interests include health disparities and community engaged research in pulmonary, critical care, and sleep medicine.
PUBLICATIONS
https://www.ncbi.nlm.nih.gov/myncbi/16kv1mLK65vkq/bibliography/public/
PROFESSIONAL SOCIETY MEMBERSHIPS
American Thoracic Society
American College of Physicians
American College of Chest Physicians
Dr. Thornton conducts population health and community-engaged research with an emphasis on testing novel interventions to improve the care of people affected by pulmonary, critical care, and sleep disorders. His funding has included the Robert Wood Johnson Foundation, Health Resources and Services Administration, and the National Institutes of Health.
PubMed Publications
- Gaps in buprenorphine access: Examining provider availability and treatment continuity Abstract: CONCLUSIONS: One in four patients experienced an interruption in buprenorphine care after their primary provider stopped prescribing buprenorphine, with rural patients particularly affected. Telehealth and other policy measures could mitigate these disruptions, ensuring more consistent OUD treatment. Further research is needed to understand provider- and patient-level factors contributing to these outcomes.
- Duration of Concurrent Oxycodone and Selective Serotonin Reuptake Inhibitors Use and the Risk of Opioid Overdose Abstract: CONCLUSION AND RELEVANCE: Prolonged concurrent use (≥14 days) of oxycodone with paroxetine or fluoxetine was associated with an increased risk of opioid overdose compared with use with other SSRIs.
- Racial and Ethnic Disparities in Cancer Mortality and Mediating Effects of Sociodemographic, Clinicopathologic, and Treatment Factors Abstract: CONCLUSIONS: Racial/ethnic disparities in cancer outcomes persist, particularly for melanoma and breast cancer among Black patients. Interventions promoting equity in cancer outcomes should be tailored by cancer type and take a multidisciplinary approach, integrating both social and biological factors to address disparities effectively.
- Perspectives of African American couples regarding participation in trials of treatments for obstructive sleep apnea Abstract: CONCLUSIONS: African American patients with OSA and their bed partners expressed several concerns regarding participation in clinical trials and offered suggestions for improving the design of clinical trials in this population.
- Capivasertib cost-effectiveness in treating advanced breast cancer: A US health care perspective Abstract: CONCLUSIONS: The findings from this study suggest that adding capivasertib to fulvestrant treatment is not cost-effective when compared with fulvestrant alone, from the perspective of the US health care system. Considering the notable therapeutic impact that the inclusion of this medication in standard treatment plans can have, it is necessary to engage in more extensive talks and negotiations over the pricing of this newly approved medication.
- Sleep Health Barriers and Facilitators Among African American Family Caregivers Abstract: CONCLUSION: Our findings inform the cultural adaptation of sleep health interventions for African American family caregivers to address stress reduction, caregiving support, and sleep apnea risk and treatment.
- Association Between Opioid Use and Emergency Department Visits for Spine-Related Disorders Abstract: CONCLUSION: We found that opioid use significantly increases the frequency of all-cause ED visits among SRD patients. These findings highlight the importance of cautious opioid prescribing among SRD patients.
- Hydrocodone Rescheduling and Opioid Prescribing Disparities in Breast Cancer Patients Abstract: Background: Pain is a prevalent issue among breast cancer patients and survivors, with a significant proportion receiving hydrocodone for pain management. However, the rescheduling of hydrocodone from Schedule III to Schedule II by the U.S. Drug Enforcement Administration (DEA) in October 2014 raised concerns about potential barriers to opioid access for cancer patients, particularly among vulnerable populations such as dually eligible Medicare-Medicaid beneficiaries and racial/ethnic...
- Association between buprenorphine adherence for opioid use disorder and clinical events and healthcare spending among older patients Abstract: CONCLUSIONS: Buprenorphine adherence was associated with reduced risks of opioid overdose, hospitalization, and healthcare spending in the overall population of older individuals with OUD. Enhancing adherence to buprenorphine should be prioritized in OUD treatment strategies among this population.
- Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019 Abstract: Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands. This study examines the burden of conditions requiring acute versus chronic care, including sequelae. Conditions and sequelae from the Global Burden of Diseases Study 2019 were classified into acute or chronic care categories. Data were analysed by age, sex, and socio-demographic index,...
- Effects of the prescription drug monitoring program mandate on queries of controlled substance prescriptions: Findings from Texas Abstract: CONCLUSION: The immediate impact of the TPMP may be limited, particularly given that the mandate's implementation coincided with the COVID-19 pandemic. To more effectively address controlled substance misuse, the state should consider strengthening the mandate and exploring additional measures to enhance its impact.
- Spotlighting Community Organizations' Pandemic Pivots: How Cleveland Continued to Serve its Vulnerable Populations During COVID-19 Abstract: The shutdowns associated with the COVID-19 pandemic had immediate effects on nonprofit organizations, disrupting their abilities to provide resources to the vulnerable populations they serve, and leaving many residents without supports they needed. In Cleveland, Ohio, a community-based research network developed a series of publicly available podcast interview spotlights with local nonprofits during the shutdown to describe how they had shifted to continue to meet their communities' needs. The...
- Concurrent Depression Management in Patients with Opioid Use Disorder Undergoing Buprenorphine Therapy: Association with Buprenorphine Discontinuation Abstract: Objective: The relationship between concurrent depression and Opioid Use Disorder (OUD) treatment outcomes remains incompletely understood. Prior studies found mixed results regarding the impact of psychiatric comorbidities on retention to medications for OUD. This study aims to evaluate how the receipt of pharmacotherapy for depression impacts retention to buprenorphine therapy among patients with OUD and concurrent depression. Methods: We conducted a retrospective cohort study using the Humana...
- Building the capacity of early-stage investigators to conduct community-engaged health disparities research Abstract: This paper describes an NIH funded Pilot Awards Program in Cleveland, Ohio, focused on developing the capacity of new and early-stage academic investigators to conduct community-engaged research. After a competitive application process, the program selected 18 early-stage investigators (post-doctoral fellows and junior faculty) who had partnered with at least one community organization to conduct pilot health disparities research projects, awarding up to $50,000 per project for one year. The...
- Early-stage investigators' experiences with an National Institutes of Health Pilot Award Program Abstract: CONCLUSIONS: Future programs helping ESIs who conduct community-engaged research to launch their research careers should consider implementing tailored support while offering strategies to eliminate or reduce institutional barriers, including strengthening mentoring.
Education & Training
Education
Residency
University of Washington (Seattle) – Internal MedicineFellowship
University of Washington (Seattle) – ResearchGraduate School
University of Washington (Seattle) MPHFellowship
University of Washington (Seattle) – Pulmonary MedicineInternship
University of Washington (Seattle) – Internal MedicineMedical Education
Washington University School of Medicine (Missouri) MD